General
Preferred name
HYPERICIN
Synonyms
Hypericine ()
Cyclosan ()
Hyp, HY ()
SGX301 ()
NSC-407313 ()
Hipericin ()
Hypericum red ()
SGX-301 ()
P&D ID
PD071021
CAS
548-04-9
Tags
drug candidate
natural product
available
Drug Status
investigational
Max Phase
Phase 3
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Cell lines
1
Organisms
1
Compound Sets
10
AdooQ Bioactive Compound Library
A12069
ChEMBL Drugs
CHEMBL286494
Drug Repurposing Hub
DrugBank
DB13014
DrugMatrix
Ki Database
hypericin
MedChem Express Bioactive Compound Library
HY-N0453
ReFrame library
Selleckchem Bioactive Compound Library
hypericin
TargetMol Bioactive Compound Library
T6S0923
External IDs
32
Properties
(calculated by RDKit )
Molecular Weight
504.08
Hydrogen Bond Acceptors
8
Hydrogen Bond Donors
6
Rotatable Bonds
0
Ring Count
8
Aromatic Ring Count
8
cLogP
5.08
TPSA
155.52
Fraction CSP3
0.07
Chiral centers
0.0
Largest ring
6.0
QED
0.12
Structural alerts
2
aggregator (Aggregator Advisor)
Aggregators
aggregator (ZINC)
Aggregators
Related compounds
Custom attributes
(extracted from source data)
Pathway
Microbiology&virology
Tyrosine Kinase/Adaptors
Anti-infection
Apoptosis
Cell Cycle/DNA Damage
Epigenetics
Metabolic Enzyme/Protease
Neuronal Signaling
TGF-beta/Smad
Target
Antibacterial
Antiviral
Tyrosine Kinases
antibiotic
Cytochrome P450
Dopamine β-hydroxylase
Influenza Virus
Monoamine Oxidase
PKC
Reverse Transcriptase
Telomerase
Hydroxylase,MAO,P450 (e.g. CYP17),PKC,Reverse Transcriptase,Telomerase
MOA
tyrosine kinase inhibitor
Source data