General
Preferred name
HEPES
Synonyms
4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid ()
HEPES Sodium ()
P&D ID
PD070505
CAS
75277-39-3
103404-87-1
7365-45-9
Tags
available
covalent binder
drug candidate
Drug Status
investigational
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE 29
PRICE 29
DESCRIPTION HEPES Sodium salt is a nonvolatile zwitterionic chemical buffering agent. HEPES Sodium salt is broadly applied in cell culture. HEPES Sodium salt is effective at pH 6.8 to 8.2. HEPES Sodium salt also induces of lysosome biogenesis.
DESCRIPTION HEPES is a zwitterionic sulfonic acid buffering agent, commonly used to uphold a neutral pH of basal medium within cell cultures. (Enamine Bioactive Compounds)
DESCRIPTION HEPES is a zwitterionic sulfonic acid buffering agent, commonly used to uphold a neutral pH of basal medium within cell cultures.HEPES is a potent inducer of lysosome biogenesis. (TargetMol Bioactive Compound Library)
Compound Sets
6
CovBinderInPDB
CBR004082
CBR004378
CBR004379
CBR004380
CBR004381
DrugBank
DB16872
Enamine Bioactive Compounds
EBC-155071
Other bioactive compounds
Selleckchem Bioactive Compound Library
hepes
TargetMol Bioactive Compound Library
T8549
External IDs
51
Properties
(calculated by RDKit )
Molecular Weight
238.1
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
2
Rotatable Bonds
5
Ring Count
1
Aromatic Ring Count
0
cLogP
-1.52
TPSA
81.08
Fraction CSP3
1.0
Chiral centers
0.0
Largest ring
6.0
QED
0.57
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Source data