General
Preferred name
PD070274
Synonyms
1-Methylpsilocin ()
3-(2-Dimethylamino-ethyl)-1-methyl-1H-indol-4-ol ()
P&D ID
PD070274
CAS
1465-16-3
Tags
available
drug candidate
Drug indication
Discovery agent
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
1-Methylpsilocin is a potent and selective 5-HT2C agonist (IC50= 12 and 633 nM for 5-HT2C and 5-HT2A receptors respectively). It is acting at 5-HT2A sites but is inactive at the 5-HT1A receptor.\
(BOC Sciences Bioactive Compounds)
DESCRIPTION
Selective CysLT1 antagonist; also TREK2 activator
(Tocris Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
3
BOC Sciences Bioactive Compounds
DrugMAP
Tocris Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
11
Molecular Weight
218.14
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
3
Ring Count
2
Aromatic Ring Count
2
cLogP
1.99
TPSA
28.4
Fraction CSP3
0.38
Chiral centers
0.0
Largest ring
6.0
QED
0.85
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Primary Target
5-HT2C Receptors
MOA
Agonist
Source data
