General
Preferred name
PD069854
Synonyms
1,3-Dipalmitoyl-rac-glycerol ()
1,3-Dipalmitin ()
1,3-Dipalmitoyl Glycerol ()
P&D ID
PD069854
CAS
502-52-3
Tags
natural product
available
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
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[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
1,3-Dipalmitoyl-rac-glycerol is a diacylglycerol that contains palmitic acid at the sn-1 and sn-3 positions. It activates protein kinase C α (PKCα) in vitro (Ka = 3.8 μM). 1,3-Dipalmitoyl-rac-glycerol (0.25-2 μM) inhibits apoptosis and production of reactive oxygen species (ROS) and pro-inflammatory mediators induced by oxygen-glucose deprivation and reperfusion (OGD/R) in SH-SY5Y neuroblastoma cells. An acyl acceptor for the unspecific bifunctional wax ester synthase/acyl-CoA:Diacylglycerol acyltransferase.
(BOC Sciences Bioactive Compounds)
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[[ compound.targets[tid].gene_name ]]
Compound Sets
2
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
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[[ ligand_id ]]
free of charge
External IDs
23
Molecular Weight
568.51
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
1
Rotatable Bonds
32
Ring Count
0
Aromatic Ring Count
0
cLogP
10.4
TPSA
72.83
Fraction CSP3
0.94
Chiral centers
0.0
Largest ring
0.0
QED
0.06
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Source data
