General
Preferred name
EPLIVANSERIN
Synonyms
Eplivanserin (mixture) ()
SR-46349 (mixture) ()
Eplivanserin hemifumarate ()
SR46349B ()
EPLIVANSERIN FUMARATE ()
SR-46349 ()
SR46349 ()
SR-46349B ()
P&D ID
PD069584
CAS
130580-02-8
130579-75-8
130581-13-4
Tags
available
drug candidate
Drug indication
Sleep-wake disorder
Primary insomnia
Schizophrenia
Drug Status
investigational
Max Phase
Phase 3
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Selective GPR55 antagonist
(Tocris Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
7
Axon Medchem Screening Library
ChEMBL Drugs
DrugBank
DrugMAP
MedChem Express Bioactive Compound Library
Other bioactive compounds
Tocris Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
33
Molecular Weight
328.16
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
1
Rotatable Bonds
7
Ring Count
2
Aromatic Ring Count
2
cLogP
3.53
TPSA
45.06
Fraction CSP3
0.21
Chiral centers
0.0
Largest ring
6.0
QED
0.48
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Serotonin Transporter
5-HT Receptor
5-HT2A antagonist
Pathway
Neuronal Signaling
GPCR/G protein
Primary Target
5-HT2A Receptors
MOA
Antagonist
Source data
