General
Preferred name
AMIFLOXACIN
Synonyms
Win49375 ()
AMIFLOXACIN MESYLATE ()
WIN-49,375 ()
WIN 49,375 ()
WIN-49375 ()
Amifloxacine ()
Amifloxacino ()
WIN 49,375-3 ()
Amifloxacin mesilate ()
WIN-49375-3 ()
P&D ID
PD068217
CAS
86393-37-5
88036-80-0
Tags
available
drug candidate
Drug Status
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Amifloxacin (WIN 49375) is a fluoroquinolone type II DNA topoisomerase (DNA gyrase) inhibitor antibacterial .
(GtoPdb)
PRICE
364
DESCRIPTION
Amifloxacin (Win49375) is a synthetic antibacterial compound demonstrating moderate activity against Staphylococcus aureus, with MICs ?? 2 micrograms/ml.
DESCRIPTION
Amifloxacin (Win49375) is a synthetic antibacterial compound demonstrating moderate activity against Staphylococcus aureus, with MICs ≤ 2 micrograms/ml.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
7
ChEMBL Drugs
DrugMAP
DrugMatrix
Guide to Pharmacology
MedChem Express Bioactive Compound Library
ReFrame library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
24
Molecular Weight
334.14
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
3
Aromatic Ring Count
2
cLogP
0.76
TPSA
77.81
Fraction CSP3
0.38
Chiral centers
0.0
Largest ring
6.0
QED
0.86
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
S. aureus
Bacterial
Pathway
Microbiology/virology
Anti-infection
Source data
