General
Preferred name
OXMETIDINE
Synonyms
Oxmetidine FA(72830-39-8 Free base) ()
SKF 92994 ()
Oxmetidina ()
Oxmetidinum ()
Oxmetidine FA ()
OXMETIDINE MESYLATE ()
Oxmetidine Hydrochloride ()
SK&F-92994-A2 ()
SK&F 92994-A(SUB 2) ()
SKF-92994-A2 ()
SK&F 92994-A2 ()
Oxmetidine hcl ()
SK&F 92994-J2 ()
SK&F-92994-J2 ()
SKF-92994-J2 ()
Oxmetidine mesilate ()
P&D ID
PD067929
CAS
63204-23-9
72830-39-8
Tags
available
drug candidate
Drug Status
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
1144
PRICE
120
DESCRIPTION
Oxmetidine (SKF 92994) is a novel H2 receptor antagonist that is cytotoxic. Oxmetidine inhibits transmembrane calcium flux in cardiac and vascular tissues and is used in the treatment of active duodenal ulcers.
(TargetMol Bioactive Compound Library)
DESCRIPTION
Oxmetidine FA is an orally available specific histamine H2 receptor antagonist with antiulcerogenic properties.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
4
ChEMBL Drugs
DrugMatrix
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
27
Molecular Weight
399.14
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
3
Rotatable Bonds
8
Ring Count
4
Aromatic Ring Count
3
cLogP
2.47
TPSA
104.92
Fraction CSP3
0.32
Chiral centers
0.0
Largest ring
6.0
QED
0.5
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Immunology/Inflammation
Neuroscience
Target
Histamine Receptor
H2 receptor
Source data
