General
Preferred name
ALVAMELINE
Synonyms
Lu 25-109 ()
ALVAMELINE MALEATE ()
Alvamelina ()
LU 25-109-M ()
LU-25-109-M ()
P&D ID
PD067499
CAS
120241-31-8
219581-36-9
Tags
available
drug candidate
Drug indication
Alzheimer disease
Drug Status
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
4
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
21
Properties
(calculated by RDKit )
Molecular Weight
193.13
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
0
Rotatable Bonds
2
Ring Count
2
Aromatic Ring Count
1
cLogP
0.41
TPSA
46.84
Fraction CSP3
0.67
Chiral centers
0.0
Largest ring
6.0
QED
0.68
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
mAChR
Pathway
Neuronal Signaling
GPCR/G protein
Source data
