General
Preferred name
ELINAFIDE
Synonyms
ELINAFIDE MESILATE ()
LU 79553 ()
Elinafida ()
LU-79553 ()
P&D ID
PD067269
CAS
162706-37-8
Tags
available
drug candidate
Drug Status
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
93
DESCRIPTION
Elinafide, an isoquinoline derivative, has been found to be a Type II DNA topoisomerase inhibitor that was once developed in anticancer studies.
(BOC Sciences Bioactive Compounds)
DESCRIPTION
Elinafide, a dinaphthylimide cytotoxic agent, is a DNA-targeted anticancer agent that has shown antitumor activity in in vitro and in vivo assays.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
9
Organisms
0
Compound Sets
6
BOC Sciences Bioactive Compounds
ChEMBL Drugs
DrugMatrix
MedChem Express Bioactive Compound Library
ReFrame library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
16
Molecular Weight
520.21
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
2
Rotatable Bonds
10
Ring Count
6
Aromatic Ring Count
4
cLogP
3.45
TPSA
98.82
Fraction CSP3
0.23
Chiral centers
0.0
Largest ring
6.0
QED
0.25
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
DNA
Topoisomerase
Pathway
Cell Cycle/DNA Damage
DNA Damage/DNA Repair
Source data
