General
Preferred name
pemafibrate
Synonyms
(R)-K-13675 ()
K-13675, (r)- ()
P&D ID
PD064903
CAS
848259-27-8
Tags
available
drug
Approved by
PMDA
First approval
2017
Drug indication
Cardiovascular disease
Lipid metabolism disorder
Hyperlipidemia
Drug Status
investigational
approved
Max Phase
Phase 3
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
8
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
18
Properties
(calculated by RDKit )
Molecular Weight
490.21
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
1
Rotatable Bonds
13
Ring Count
4
Aromatic Ring Count
4
cLogP
5.55
TPSA
94.26
Fraction CSP3
0.29
Chiral centers
1.0
Largest ring
6.0
QED
0.24
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
PPAR
hPPAR??
human PPAR??
PPAR??
Pathway
Cell Cycle/DNA Damage
DNA Damage/DNA Repair
Metabolism
MOA
PPAR receptor agonist
Source data
