General
Preferred name
NICOTINAMIDE RIBOSIDE
Synonyms
Nicotinamide Riboside Chloride ()
Nicotinamide riboside (chloride) ()
Nicotinamide riboside ()
Ribosylnicotinamide ()
Nicotinamide ribonucleoside ()
Nicotinamide riboside-d4 (triflate) ()
P&D ID
PD064890
CAS
1341-23-7
23111-00-4
Tags
available
drug candidate
Drug indication
Mitochondrial myopathy
Drug Status
investigational
Max Phase
Phase 3
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Dipeptidyl peptidase IV (DPP-IV) inhibitor (Tocris Bioactive Compound Library)
Compound Sets
11
AdooQ Bioactive Compound Library
A22018
Cayman Chemical Bioactives
36941
34311
ChEMBL Drugs
CHEMBL438497
DrugBank
DB14933
DrugMAP
DMJBYSE
MedChem Express Bioactive Compound Library
HY-123033A
Novartis Chemogenetic Library (NIBR MoA Box)
ReFrame library
Selleckchem Bioactive Compound Library
nicotinamide-riboside-chloride
TargetMol Bioactive Compound Library
T13795
Tocris Bioactive Compound Library
6018
External IDs
41
Properties
(calculated by RDKit )
Molecular Weight
255.1
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
4
Rotatable Bonds
3
Ring Count
2
Aromatic Ring Count
1
cLogP
-2.32
TPSA
116.89
Fraction CSP3
0.45
Chiral centers
4.0
Largest ring
6.0
QED
0.45
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Chromatin/Epigenetic
DNA Damage/DNA Repair
Cell Cycle/DNA Damage
Epigenetics
Metabolic Enzyme/Protease
Target
SIRT1
SIRT3
Endogenous Metabolite
Sirtuin
Primary Target
Other Kinases
MOA
Substrate
Member status
member
Source data