General
Preferred name
ISORHYNCHOPHYLLINE
Synonyms
Isorhyncophylline ()
IsoRhy ()
Isorhychophylline ()
7-Isorhyncophylline ()
IsoRhy, 7-Isorhyncophylline ()
P&D ID
PD063690
CAS
6859-01-4
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Isorhynchophylline is an alkaloid isolated from Crocus sativus with anticancer, antihypertensive, anti-inflammatory, and neuroprotective properties. Isorhynchophylline can be applied to cardiovascular and neurological disorders, and cancer studies[1][2][3][4][5][6][7][8][9][10][11][12][13].
PRICE 65
DESCRIPTION 1. Isorhynchophylline (7-Isorhyncophylline) and rhyncophylline can directly inhibit the contractile responses induced by several agonists in small blood vessels of rat, they also can inhibit the hypertensive effect of angiotensin ??.
DESCRIPTION 1. Isorhynchophylline (7-Isorhyncophylline) and rhyncophylline can directly inhibit the contractile responses induced by several agonists in small blood vessels of rat, they also can inhibit the hypertensive effect of angiotensin Ⅱ. (TargetMol Bioactive Compound Library)
Compound Sets
5
AdooQ Bioactive Compound Library
A14751
Cayman Chemical Bioactives
29650
MedChem Express Bioactive Compound Library
HY-N0766
Selleckchem Bioactive Compound Library
isorhychophylline
TargetMol Bioactive Compound Library
T6S0657
External IDs
19
Properties
(calculated by RDKit )
Molecular Weight
384.2
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
1
Rotatable Bonds
4
Ring Count
4
Aromatic Ring Count
1
cLogP
2.7
TPSA
67.87
Fraction CSP3
0.55
Chiral centers
4.0
Largest ring
6.0
QED
0.49
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
NF-κB
SOD
Autophagy
Pathway
Immunology/Inflammation
NF-¦ÊB
Source data