General
Preferred name
(+)-1-(1,2-DIPHENYLETHYL)PIPERIDINE
Synonyms
(±)-1-(1,2-Diphenylethyl)piperidine maleate ()
Diphenidine hydrochloride ()
Diphenidine (hydrochloride) ()
P&D ID
PD063477
CAS
28383-15-5
207461-99-2
Tags
available
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Diphenidine is a homeomorph of the NMDA receptor channel blocker, MK 801, that has been identified as a designer drug. It has been studied as a neuroprotective agent for the treatment of brain injury following hypoxia.
(BOC Sciences Bioactive Compounds)
DESCRIPTION
NMDA antagonist, acts ion channel site
(Tocriscreen Total)
DESCRIPTION
The meleate salt form of (±)-1-(1,2-Diphenylethyl)piperidine, which has been found to be a high affinity antagonist at the ion channel on the NMDA receptor.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
4
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
DrugMatrix
Tocriscreen Total
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
30
Molecular Weight
265.18
Hydrogen Bond Acceptors
1
Hydrogen Bond Donors
0
Rotatable Bonds
4
Ring Count
3
Aromatic Ring Count
2
cLogP
4.46
TPSA
3.24
Fraction CSP3
0.37
Chiral centers
1.0
Largest ring
6.0
QED
0.79
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Source data
