General
Preferred name
PD063436
Synonyms
3-Methyl-GABA ()
P&D ID
PD063436
CAS
1216629-00-3
62306-84-7
71424-95-8
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION 3-Methyl-GABA is a potent GABA aminotransferase activator. 3-Methyl-GABA can fit the binding pocket of GABAA receptor (GABAaR). 3-Methyl-GABA can activate L-glutamic acid decarboxylase (GAD). 3-Methyl-GABA has anticonvulsant activity[1][2].
DESCRIPTION Benzodiazepine inverse agonist; putative endogenous ligand (Tocris Bioactive Compound Library)
DESCRIPTION 3-Methyl-GABA is an activator of GABA aminotransferase. (BOC Sciences Bioactive Compounds)
DESCRIPTION Activator of GABA amino-transferase (Tocriscreen Total)
Compound Sets
6
BOC Sciences Bioactive Compounds
3-methyl-gaba-cas-71424-95-8-item-223597
Enamine BioReference Compounds
MedChem Express Bioactive Compound Library
HY-115685
Other bioactive compounds
Tocris Bioactive Compound Library
0386
Tocriscreen Total
External IDs
25
Properties
(calculated by RDKit )
Molecular Weight
117.08
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
0
Aromatic Ring Count
0
cLogP
0.06
TPSA
63.32
Fraction CSP3
0.8
Chiral centers
1.0
Largest ring
0.0
QED
0.55
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
GABA Receptor
Primary Target
Miscellaneous GABA
Pathway
Membrane Transporter/Ion Channel
Neuronal Signaling
Source data