General
Preferred name
PD063436
Synonyms
3-Methyl-GABA ()
4-Amino-3-methylbutanoic acid hydrochloride ()
P&D ID
PD063436
CAS
1216629-00-3
62306-84-7
71424-95-8
Tags
available
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
3-Methyl-GABA is a potent GABA aminotransferase activator. 3-Methyl-GABA can fit the binding pocket of GABAA receptor (GABAaR). 3-Methyl-GABA can activate L-glutamic acid decarboxylase (GAD). 3-Methyl-GABA has anticonvulsant activity[1][2].
DESCRIPTION
Benzodiazepine inverse agonist; putative endogenous ligand
(Tocris Bioactive Compound Library)
DESCRIPTION
3-Methyl-GABA is an activator of GABA aminotransferase.
(BOC Sciences Bioactive Compounds)
DESCRIPTION
Activator of GABA amino-transferase
(Tocriscreen Total)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
7
BOC Sciences Bioactive Compounds
Enamine Bioactive Compounds
Enamine BioReference Compounds
MedChem Express Bioactive Compound Library
Other bioactive compounds
Tocris Bioactive Compound Library
Tocriscreen Total
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
29
Molecular Weight
117.08
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
0
Aromatic Ring Count
0
cLogP
0.06
TPSA
63.32
Fraction CSP3
0.8
Chiral centers
1.0
Largest ring
0.0
QED
0.55
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Primary Target
Miscellaneous GABA
Pathway
Membrane Transporter/Ion Channel
Neuronal Signaling
Target
GABA Receptor
Source data
