General
Preferred name
AMELTOLIDE
Synonyms
LY-201116 ()
ADD 75073 ()
LY 201116 ()
Ameltolida ()
P&D ID
PD063402
CAS
787-93-9
Tags
available
drug candidate
Drug indication
Epileptic seizures
Drug Status
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
29
DESCRIPTION
Ameltolide has binding affinity to voltage-gated sodium channel.
(Enamine Bioactive Compounds)
DESCRIPTION
Ameltolide is an anticonvulsant agent. It has been shown to be effective at inhibiting seizures in animal models.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
8
ChEMBL Drugs
Drug Repurposing Hub
DrugMAP
DrugMatrix
Enamine Bioactive Compounds
MedChem Express Bioactive Compound Library
ReFrame library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
23
Molecular Weight
240.13
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
2
Ring Count
2
Aromatic Ring Count
2
cLogP
3.14
TPSA
55.12
Fraction CSP3
0.13
Chiral centers
0.0
Largest ring
6.0
QED
0.79
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
MOA
anticonvulsant
Target
Drug Derivative
Source data
