General
Preferred name
AM-24
Synonyms
2,4,6-Triiodophenol ()
TRIIODOPHENOL ()
2,4,6-Triiodo-Phenol(Tip) ()
P&D ID
PD063361
CAS
609-23-4
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION 2,4,6-Triiodophenol is an orally active and potent leukotriene B4 (LTB4) synthesis inhibitor. 2,4,6-Triiodophenol can induce mouse blastocysts apoptosis[1][2].
PRICE 42
DESCRIPTION 2,4,6-Triiodophenol exhibits binding affinity to transthyretin. (Enamine Bioactive Compounds)
DESCRIPTION 2,4,6-Triiodophenol is used as an iodinated disinfection by product formed during chlorination of sewage effluents. It is also used as a potent thyroid disrupting chemical and to investigate deiodinase (TargetMol Bioactive Compound Library)
Compound Sets
7
Drug Repurposing Hub
Enamine Bioactive Compounds
EBC-03124
Enamine BioReference Compounds
IPPI - DB
1990
MedChem Express Bioactive Compound Library
HY-W073687
ReFrame library
TargetMol Bioactive Compound Library
T8628
External IDs
23
Properties
(calculated by RDKit )
Molecular Weight
471.73
Hydrogen Bond Acceptors
1
Hydrogen Bond Donors
1
Rotatable Bonds
0
Ring Count
1
Aromatic Ring Count
1
cLogP
3.21
TPSA
20.23
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.58
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
Transthyretin (human)
ALOX5
Apoptosis
MOA
Lipoxygenase inhibitor
Source data