General
Preferred name
ZUCLOMIPHENE
Synonyms
CLOMIPHENE CITRATE ()
Clomiphene (citrate) ()
Clomifene citrate ()
Zuclomiphene (citrate) ()
NSC 35770, Clomiphene citrate ()
Zuclomifene ()
RMI 16,312 ()
RMI-16,312 ()
RMI-16312 ()
Isomer A ()
Zuclomifeno ()
Transclomiphene ()
Clomiphene cis-form ()
P&D ID
PD063092
CAS
50-41-9
207563-42-6
7619-53-6
15690-55-8
911-45-5
Tags
available
drug
nuisance
drug candidate
Drug indication
Female infertility
Drug Status
approved
investigational
Max Phase
2.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Zuclomiphene citrate is a cis isomer of Clomiphene citrate. Zuclomiphene citrate has an antiestrogenic effect and can inhibit the secretion of luteinizing hormone (LH) more than the trans isomer. Zuclomiphene citrate is also an orally active hypocholesterolemic agent[1][2][3][4].
Compound Sets
11
AdooQ Bioactive Compound Library
A10230
Cayman Chemical Bioactives
16087
ChEMBL Drugs
CHEMBL167779
CZ-OPENSCREEN Bioactive Library
Drug Repurposing Hub
DrugMAP
DMS51VC
DrugMAP Approved Drugs
DMS51VC
MedChem Express Bioactive Compound Library
HY-B1617A
Nuisance compounds in cellular assays
Selleckchem Bioactive Compound Library
Clomifene-citrate-Serophene
The Spectrum Collection
External IDs
40
Properties
(calculated by RDKit )
Molecular Weight
405.19
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
0
Rotatable Bonds
9
Ring Count
3
Aromatic Ring Count
3
cLogP
6.56
TPSA
12.47
Fraction CSP3
0.23
Chiral centers
0.0
Largest ring
6.0
QED
0.37
QED
0.37
Structural alerts
1
CAD
Nuisance compounds
Related compounds
Custom attributes
(extracted from source data)
Indication
infertility
Target
ESR1
Estrogen Receptor/ERR
Estrogen/progestogen Receptor
MOA
Estrogen Receptor antagonist
Pathway
Vitamin D Related/Nuclear Receptor
Source data