General
Preferred name
EPEREZOLID
Synonyms
PNU-100592 ()
U-100592 ()
U-100,592 ()
P&D ID
PD062885
CAS
165800-04-4
Tags
available
drug candidate
Drug indication
Bacterial infection
Antibacterial
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Eperezolid is a oxazolidinone antibacterial. It inhibits protein synthesis by blocking function of the bacterial 50S ribosomal subunit. Eperezolid is not as potent as , which was the first oxazolidinone to be approved for clinical use. (GtoPdb)
DESCRIPTION Eperezolid(PNU-100592) is a oxazolidinone antibacterial agent, Eperezolid demonstrated good in vitro inhibitory activity, regardless of methicillin susceptibility for staphylococci(MIC90= 1-4 mg/ml). (BOC Sciences Bioactive Compounds)
Compound Sets
8
BOC Sciences Bioactive Compounds
eperezolid-cas-165800-04-4-item-84-221011
ChEMBL Drugs
CHEMBL47955
Drug Repurposing Hub
DrugMAP
DMCU1WO
Guide to Pharmacology
10803
MedChem Express Bioactive Compound Library
HY-10393
ReFrame library
TargetMol Bioactive Compound Library
T15237
External IDs
21
Properties
(calculated by RDKit )
Molecular Weight
394.17
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
2
Rotatable Bonds
5
Ring Count
3
Aromatic Ring Count
1
cLogP
-0.07
TPSA
102.42
Fraction CSP3
0.5
Chiral centers
1.0
Largest ring
6.0
QED
0.72
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Antibacterial
Antibiotic
Anti-infection
Target
antibiotic
Bacterial
MOA
bacterial 30S ribosomal subunit inhibitor
Source data