General
Preferred name
NEBRACETAM
Synonyms
NEBRACETAM FUMARATE ()
WEB 1881 FU hydrochloride ()
Nebracetam (hydrochloride) ()
WEB 1881 FU (hydrochloride) ()
Nebracetam hydrochloride ()
P&D ID
PD062424
CAS
116041-13-5
97205-34-0
1177279-49-0
Tags
available
drug candidate
Drug indication
Parkinson disease
Drug Status
investigational
Max Phase
2.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Nebracetam hydrochloride, a nootropic M1-muscarinic agonist, induces a rise of intracellular Ca2+ concentration. Nebracetam hydrochloride exhibits an EC50 of 1.59 mM for elevating [Ca2+]i[1].
PRICE 34
DESCRIPTION Nebracetam hydrochloride is a nootropic M1-muscarinic agonist, induces a rise of intracellular Ca2+ concentration. (Enamine Bioactive Compounds)
DESCRIPTION Nebracetam hydrochloride (WEB 1881 FU hydrochloride) is an agonist nootropic M1-muscarinic. Nebracetam hydrochloride induces a rise of intracellular Ca2+ concentration. Nebracetam hydrochloride exhibits an EC50 of 1.59 mM for elevating [Ca2+]i. (TargetMol Bioactive Compound Library)
Compound Sets
8
ChEMBL Drugs
CHEMBL2104682
DrugMAP
DMFD249
DrugMatrix
Enamine Bioactive Compounds
EBC-181233
Enamine BioReference Compounds
MedChem Express Bioactive Compound Library
HY-113970A
ReFrame library
TargetMol Bioactive Compound Library
T12201
External IDs
20
Properties
(calculated by RDKit )
Molecular Weight
204.13
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
3
Ring Count
2
Aromatic Ring Count
1
cLogP
0.99
TPSA
46.33
Fraction CSP3
0.42
Chiral centers
1.0
Largest ring
6.0
QED
0.8
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
mAChR
mAChR M1
Pathway
Neuroscience
GPCR/G protein
Neuronal Signaling
Source data