General
Preferred name
DIFENOCONAZOLE
Synonyms
Difenoconazol ()
Difenoconazole-d6 (hydrochloride) ()
P&D ID
PD061748
CAS
119446-68-3
2748435-81-4
Tags
available
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
29
DESCRIPTION
Difenoconazole is a sterol demethylation inhibitor, as a fungicide. Difenoconazole binds the heme portion of the fungal cytochrome P450 51, interferes the mycelial growth and inhibits the spore germination of pathogens, suppressing fungal growth[1].
DESCRIPTION
Difenoconazole is a broad-spectrum triazole fungicide that inhibits ergosterol biosynthesis via inhibition of the cytochrome P450-dependent 14??-demethylation of lanosterol, which results in disruption of the fungal cell membrane and cell death.
DESCRIPTION
Pestanal is a broad spectrum fungicide.
(BOC Sciences Bioactive Compounds)
DESCRIPTION
Difenoconazole is a sterol demethylation inhibitor, as a fungicide. Difenoconazole binds the heme portion of the fungal cytochrome P450 51, interferes the mycelial growth and inhibits the spore germination of pathogens, suppressing fungal growth.
(Enamine Bioactive Compounds)
DESCRIPTION
Difenoconazole is a broad-spectrum triazole fungicide that inhibits ergosterol biosynthesis via inhibition of the cytochrome P450-dependent 14α-demethylation of lanosterol, which results in disruption of the fungal cell membrane and cell death.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
3
Compound Sets
6
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
21
Molecular Weight
405.06
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
0
Rotatable Bonds
5
Ring Count
4
Aromatic Ring Count
3
cLogP
4.67
TPSA
58.4
Fraction CSP3
0.26
Chiral centers
2.0
Largest ring
6.0
QED
0.62
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Disease
KINETOPLASTIDS
Pathway
Microbiology/virology
Anti-infection
Target
Fungal
Source data
