General
Preferred name
CAREBASTINE
Synonyms
Carebastine-d5 ()
P&D ID
PD061099
CAS
90729-42-3
1189661-02-6
Tags
available
drug candidate
Drug indication
Ocular allergy
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Carebastine is the active first-pass metabolite of Ebastine. Carebastine acts as a selective histamine H1 receptor antagonist that has the potential for allergy therapy.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
8
BOC Sciences Bioactive Compounds
ChEMBL Drugs
Drug Repurposing Hub
DrugMAP
DrugMatrix
MedChem Express Bioactive Compound Library
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
23
Molecular Weight
499.27
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
1
Rotatable Bonds
11
Ring Count
4
Aromatic Ring Count
3
cLogP
6.28
TPSA
66.84
Fraction CSP3
0.38
Chiral centers
0.0
Largest ring
6.0
QED
0.31
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
HRH1
Histamine Receptor
Macrophage migration inhibitory factor (MIF)
MOA
Histamine Receptor antagonist
Pathway
GPCR/G protein
Immunology/Inflammation
Neuronal Signaling
Source data
