General
Preferred name
Alpha-Cyclodextrin (Cyclohexa-Amylose)
Synonyms
ALFADEX ()
NSC269470 ()
NSC 269470 ()
NSC-269470 ()
?-Cyclodextrin ()
α-Cyclodextrin ()
Cyclohexapentylose ()
¦Á-Cyclodextrin ()
?-Cyclodextrin (hydrate) ()
Ins-457 ()
.alpha.-cyclodextrin ()
Cavamax w6 ()
Cavamax w 6 food ()
Alpha-schardinger dextrin ()
Alpha-dextrin ()
Cyclohexaamylose ()
Ins no.457 ()
Alpha cyclodextrin ()
Oristar acd ()
Dexy pearl .alpha.-100 ()
ALPHA-CYCLODEXTRIN ()
E-457 ()
Celdex a 100 ()
Cyclomaltohexaose ()
Ringdex-a ()
P&D ID
PD060221
CAS
10016-20-3
51211-51-9
Tags
available
drug candidate
Drug Status
experimental
investigational
Max Phase
2.0
Drug indication
Prostate cancer
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION ¦Á-Cyclodextrin (¦Á-CD) is a soluble fiber derived from corn. ¦Á-Cyclodextrin can deplete sphingolipids and phospholipids from cell membranes. ¦Á-Cyclodextrin interacts with tubulin. ¦Á-Cyclodextrin improves defenses against SARS-CoV-2 infection. ¦Á-Cyclodextrin enhances the anticancer efficacy of Crcumin (HY-N0005) against breast, lung and cervical cancer. ¦Á-Cyclodextrin has beneficial effects on body weight and blood lipids[1][2][3][4][5].
DESCRIPTION α-Cyclodextrin (Alfadex) is a soluble fiber derived from corn and has beneficial effects on weight management in obese individuals with type 2 diabetes. (TargetMol Bioactive Compound Library)
Compound Sets
6
Cayman Chemical Bioactives
31219
ChEMBL Drugs
CHEMBL1230813
DrugBank
DB01909
MedChem Express Bioactive Compound Library
HY-B1513
Selleckchem Bioactive Compound Library
alpha-cyclodextrin
TargetMol Bioactive Compound Library
T17303
External IDs
43
Properties
(calculated by RDKit )
Molecular Weight
972.32
Hydrogen Bond Acceptors
30
Hydrogen Bond Donors
18
Rotatable Bonds
6
Ring Count
22
Aromatic Ring Count
0
cLogP
-13.05
TPSA
474.9
Fraction CSP3
1.0
Chiral centers
30.0
Largest ring
30.0
QED
0.12
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Microtubule/Tubulin
SARS-CoV
Pathway
Anti-infection
Cell Cycle/DNA Damage
cytoskeleton
Source data