General
Preferred name
dGTP
Synonyms
2'-Deoxyguanosine-5'-Triphosphate ()
Deoxyguanosine 5-triphosphate ()
2'-Deoxyguanosine-5'-triphosphate trisodium salt ()
dGTP trisodium salt ()
Deoxyguanosine triphosphate trisodium salt ()
DEOXYGUANOSINE TRIPHOSPHATE ()
2'-Deoxyguanosine-5'-O-triphosphate (sodium salt) ()
P&D ID
PD060117
CAS
93919-41-6
2564-35-4
Tags
available
drug candidate
Drug Status
experimental
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE 499
PRICE 41
DESCRIPTION dGTP (2'-Deoxyguanosine-5'-triphosphate) is a guanosine nucleotide highly susceptible to oxidative damage, resulting in 8-O-GDP, 8-O-dGTP, 8-O-GTP, and 8-O-dGTP. (TargetMol Bioactive Compound Library)
DESCRIPTION Deoxyguanosine triphosphate trisodium salt (2'-Deoxyguanosine-5'-triphosphate trisodium salt) is a nucleotide precursor for DNA synthesis in cells and can be used in the reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification. (TargetMol Bioactive Compound Library)
Compound Sets
3
Cayman Chemical Bioactives
35771
DrugBank
DB02181
TargetMol Bioactive Compound Library
T40192
T36688
External IDs
51
Properties
(calculated by RDKit )
Molecular Weight
507.0
Hydrogen Bond Acceptors
13
Hydrogen Bond Donors
7
Rotatable Bonds
8
Ring Count
3
Aromatic Ring Count
2
cLogP
-1.31
TPSA
278.87
Fraction CSP3
0.5
Chiral centers
5.0
Largest ring
6.0
QED
0.2
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
DNA/RNA Synthesis
Nucleoside antimetabolite/analog
Pathway
Cell Cycle/Checkpoint
DNA Damage/DNA Repair
Source data