General
Preferred name
Rhamnose
Synonyms
Rhamnose (monohydrate) ()
L-Rhamnose ()
L-Rhamnose (monohydrate) ()
Rhamnose monohydrate ()
P&D ID
PD059745
CAS
3615-41-6
10030-85-0
Tags
available
drug candidate
Drug Status
experimental
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Rhamnose (L-Rhamnose ) is an orally active deoxysugar. Rhamnose can inhibit levels of pro-inflammatory interleukin and matrix metalloproteinases (MMPs) in skin aging models. Rhamnose can promote the phosphorylation levels of PKA substrates and HSL in SVF-derived adipocytes, stimulating PKA signaling. Rhamnose can act against obesity in mice by stimulating fat dopamine receptors and inducing thermogenesis. Rhamnose shows anti-aging effects. Rhamnose monohydrate can be used in the study of Ehrlich¡¯s solid tumors and sarcomas[2][3][5].
DESCRIPTION Rhamnose monohydrate (L-Rhamnose monohydrate) is an orally active deoxysugar. Rhamnose monohydrate can inhibit levels of pro-inflammatory interleukin and matrix metalloproteinases (MMPs) in skin aging models. Rhamnose can promote the phosphorylation levels of PKA substrates and HSL in SVF-derived adipocytes, stimulating PKA signaling. Rhamnose monohydrate can act against obesity in mice by stimulating fat dopamine receptors and inducing thermogenesis. Rhamnose monohydrate shows anti-aging effects. Rhamnose monohydrate can be used in the study of Ehrlich¡¯s solid tumors and sarcomas[2][3][5].
PRICE 29
DESCRIPTION Rhamnose monohydrate (L-(+)-Rhamnose Monohydrate) is a naturally-occurring deoxy sugar that is found primarily in plants and some bacteria.
Compound Sets
3
DrugBank
MedChem Express Bioactive Compound Library
Selleckchem Bioactive Compound Library
External IDs
31
Properties
(calculated by RDKit )
Molecular Weight
164.07
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
4
Rotatable Bonds
4
Ring Count
0
Aromatic Ring Count
0
cLogP
-2.35
TPSA
97.99
Fraction CSP3
0.83
Chiral centers
4.0
Largest ring
0.0
QED
0.35
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
Endogenous Metabolite
Interleukin Related
MMP
PKA
Pathway
Immunology/Inflammation
Metabolic Enzyme/Protease
Stem Cell/Wnt
TGF-beta/Smad
Source data