General
Preferred name
L-proline betaine
Synonyms
L-stachydrine ()
Proline betaine ()
N,N-Dimethyl-L-proline ()
Methyl hygrate betaine ()
Stachydrine ()
Stachydrine hydrochloride ()
Proline betaine, L-stachydrine, Methyl hygrate betaine ()
Stachydrine (hydrochloride) ()
STACHYDRINE HCL ()
P&D ID
PD059331
CAS
4136-37-2
471-87-4
Tags
available
drug candidate
Drug Status
experimental
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Stachydrine hydrochloride is the major active constituent of Leonurus artemisia, which is a potential therapy for cardiovascular diseases[2]. Stachydrine can inhibit the NF-¦ÊB signal pathway. Anti-hypertrophic activities[1].
PRICE 29
DESCRIPTION Stachydrine is a major constituent of Chinese herb leonurus heterophyllus sweet used to promote blood circulation and dispel blood stasis. Stachydrine can inhibit the NF-¦ÊB signal pathway.
PRICE 29
DESCRIPTION Stachydrine (N,N-Dimethyl-L-proline) is a major constituent of Chinese herb leonurus heterophyllus sweet used to promote blood circulation and dispel blood stasis. Stachydrine (N,N-Dimethyl-L-proline) can inhibit the NF-??B signal pathway. Stachydrine (N,N-Dimethyl-L-proline) is a biomarker for the consumption of citrus fruits.
DESCRIPTION Stachydrine Hydrochloride is an effective component that mainly extracted from the leaf of Leonurussibiricus. (TargetMol Bioactive Compound Library)
DESCRIPTION Stachydrine (N,N-Dimethyl-L-proline) is a major constituent of Chinese herb leonurus heterophyllus sweet used to promote blood circulation and dispel blood stasis. Stachydrine (N,N-Dimethyl-L-proline) can inhibit the NF-κB signal pathway. Stachydrine (N,N-Dimethyl-L-proline) is a biomarker for the consumption of citrus fruits. (TargetMol Bioactive Compound Library)
Compound Sets
5
Cayman Chemical Bioactives
20506
DrugBank
DB04284
MedChem Express Bioactive Compound Library
HY-N0738
HY-N0298
Selleckchem Bioactive Compound Library
stachydrine
TargetMol Bioactive Compound Library
T3251
T5769
External IDs
47
Properties
(calculated by RDKit )
Molecular Weight
143.09
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
0
Rotatable Bonds
1
Ring Count
1
Aromatic Ring Count
0
cLogP
-1.02
TPSA
40.13
Fraction CSP3
0.86
Chiral centers
1.0
Largest ring
5.0
QED
0.44
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
NF-¦ÊB
Metabolism
Metabolic Enzyme/Protease
Target
Endogenous Metabolite
NF-κB
p65
NF-??
Source data