General
Preferred name
Amenamevir
Synonyms
ASP2151 ()
ASP 2151 (Amenamevir) ()
ASP-2151 ()
Asp2151 ()
P&D ID
PD059017
CAS
841301-32-4
Tags
drug
natural product
available
Approved by
PMDA
First approval
2017
Drug indication
Herpes simplex virus infection
Drug Status
approved
investigational
Max Phase
3.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
14
AdooQ Bioactive Compound Library
Axon Medchem Screening Library
Cayman Chemical Bioactives
ChEMBL Drugs
CZ-OPENSCREEN Bioactive Library
Drug Repurposing Hub
DrugBank
DrugCentral
DrugCentral Approved Drugs
DrugMAP
MedChem Express Bioactive Compound Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
21
Properties
(calculated by RDKit )
Molecular Weight
482.16
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
1
Rotatable Bonds
6
Ring Count
4
Aromatic Ring Count
3
cLogP
3.15
TPSA
122.47
Fraction CSP3
0.33
Chiral centers
0.0
Largest ring
6.0
QED
0.57
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Pathway
DNA Damage/DNA Repair
Anti-infection
Target
helicase-primase
Helicase-primase inhibitor (HPI)
HSV
DNA/RNA Synthesis
MOA
helicase primase inhibitor
Source data