General
Preferred name
FALDAPREVIR
Synonyms
BI 201335 ()
FALDAPREVIR SODIUM ()
BI-201335 ()
BI201335 ()
BI-201335 NA SALT ()
BI-201335NA ()
BI-201335 SODIUM SALT ()
BI-201335 NA ()
Faldaprevir, sodium salt ()
BI 201335 NA ()
BI-201335-NA ()
Faldaprevir-d6 ()
P&D ID
PD058934
CAS
801283-95-4
2750534-88-2
Tags
available
drug candidate
Drug indication
chronic hepatitis C virus infection
Hepatitis C virus infection
Drug Status
investigational
Max Phase
3.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
1161
DESCRIPTION
Faldaprevir is an orally effective, selective, non-covalent HCV NS3/4A protease inhibitor with high inhibitory activity against HCV 1a and 1b genotypes (Ki=2.6 nM &2.0 nM).Faldaprevir inhibits viral replication by blocking the breakdown of viral precursor proteins, and is well tolerated with good antiviral activity against hepatitis C virus.
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
1
Compound Sets
4
Cayman Chemical Bioactives
ChEMBL Drugs
DrugBank
DrugMAP
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
36
Molecular Weight
868.25
Hydrogen Bond Acceptors
11
Hydrogen Bond Donors
4
Rotatable Bonds
13
Ring Count
6
Aromatic Ring Count
3
cLogP
8.0
TPSA
208.85
Fraction CSP3
0.53
Chiral centers
5.0
Largest ring
6.0
QED
0.07
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Source data
