General
Preferred name
Mannose 6-phosphate
Synonyms
JUVIDEX ()
D-Mannose-6-phosphate sodium salt hydrate ()
D-Mannose-6-phosphate (sodium salt hydrate) ()
P&D ID
PD058908
CAS
3672-15-9
Tags
drug candidate
natural product
available
Drug indication
Sarcoidosis
Drug Status
investigational
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION D-Mannose-6-phosphate (M6P) is a phosphorylated aldohexose that has diverse physiological roles. It can be used to produce glucose as an energy source, converted to mannitol to serve as an osmolyte or metabolic store, or directed to the N-glycosylation pathway. M6P is also a ligand for both cation-dependent and -independent receptors and binds, as part of an N-glycan, to mannose receptor homology domains on other proteins. (BOC Sciences Bioactive Compounds)
Compound Sets
4
BOC Sciences Bioactive Compounds
d-mannose-6-phosphate-sodium-salt-hydrate-292125
Cayman Chemical Bioactives
18890
DrugBank
DB11848
DrugMAP
DMZKYNO
External IDs
19
Properties
(calculated by RDKit )
Molecular Weight
260.03
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
6
Rotatable Bonds
7
Ring Count
0
Aromatic Ring Count
0
cLogP
-3.26
TPSA
164.75
Fraction CSP3
0.83
Chiral centers
4.0
Largest ring
0.0
QED
0.2
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Source data