General
Preferred name
VELNEPERIT
Synonyms
S2367 ()
S-2367 ()
P&D ID
PD058393
CAS
342577-38-2
Tags
available
drug candidate
Drug Status
investigational
Max Phase
2.0
Drug indication
Obesity
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Velneperit (S-2367) is a novel neuropeptide Y (NPY) Y5 receptor antagonist.;Target: neuropeptide Y receptor;Velneperit (S-2367) is a once-daily, oral, centrally acting, small molecule neuropeptide Y (NPY) Y5 receptor antagonist.
PRICE
103
DESCRIPTION
Velneperit (S2367) is potent and selective neuropeptide Y (NPY) Y5 receptor under evaluating for treatment of obesity.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
8
Cayman Chemical Bioactives
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
ReFrame library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
17
Molecular Weight
407.15
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
2
Rotatable Bonds
4
Ring Count
2
Aromatic Ring Count
1
cLogP
3.32
TPSA
88.16
Fraction CSP3
0.65
Chiral centers
0.0
Largest ring
6.0
QED
0.8
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Neuroscience
Neuronal Signaling
Target
NPY5R
Neuropeptide Y Receptor
neuropeptide Y (NPY) receptor
neuropeptide Y (NPY) Y5 receptor
MOA
neuropeptide receptor antagonist
Source data
