General
Preferred name
ISOXAFLUTOLE
Synonyms
RP 201772 ()
Merlin ()
RP-201772 ()
RP201772 ()
Balance ()
RPA-201772 ()
264-EUP-99 ()
P&D ID
PD058351
CAS
141112-29-0
Tags
drug
available
Drug Status
approved
experimental
investigational
Max Phase
2.0
Drug indication
Herpes Labialis
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
29
DESCRIPTION
Isoxaflutole (Merlin; RP-201772) is a selective herbicide for pre-emergence control of a wide range of important broadleaf and grass weeds in corn and sugarcane. Isoxaflutole is a precursor and delivery vector of diketonitrile (DKN), which is an inhibitor for 4-hydroxyphenylpyruvate dioxygenase (HPPD), leads to a characteristic bleaching of susceptible species[1].
DESCRIPTION
Isoxaflutole (RP-201772) is a low toxic herbicide and has been marketed as a substitute for atrazine.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
5
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
MedChem Express Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
26
Molecular Weight
359.04
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
0
Rotatable Bonds
4
Ring Count
3
Aromatic Ring Count
2
cLogP
3.21
TPSA
77.24
Fraction CSP3
0.33
Chiral centers
0.0
Largest ring
6.0
QED
0.78
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Herbicide
HPPD
Pathway
Metabolic Enzyme/Protease
Source data
