General
Preferred name
Glyceryl Trioleate
Synonyms
Glycerol trioleate ()
Glycerine Trioleate ()
1,2,3-Trioleoyl-rac-glycerol ()
Triolein ()
1,2,3-Trioleoyl Glycerol ()
1,2,3-Trioleoyl Glycerol-d5 ()
P&D ID
PD058286
CAS
122-32-7
60892-83-3
Tags
available
drug candidate
Drug Status
investigational
Max Phase
2.0
Drug indication
adrenoleukodystrophy
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Triolein is a symmetric triacylglycerol that reduces upregulation of MMP-1 and has strong antioxidant and anti-inflammatory activities[1][2].
PRICE
29
DESCRIPTION
Glyceryl Trioleate has been investigated for the treatment of Adrenoleukodystrophy.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
6
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
38
Molecular Weight
884.78
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
0
Rotatable Bonds
50
Ring Count
0
Aromatic Ring Count
0
cLogP
18.1
TPSA
78.9
Fraction CSP3
0.84
Chiral centers
0.0
Largest ring
0.0
QED
0.03
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Endogenous Metabolite
MMP
Interleukins,MMP,ROS
Pathway
Metabolism
Proteases/Proteasome
Metabolic Enzyme/Protease
Source data
