General
Preferred name
LENABASUM
Synonyms
CPL-7075 ()
CPL7075 ()
Resunab ()
JBT-101 ()
IP-751 ()
HU-239 ()
Ajulemic Acid ()
CT-3 ()
P&D ID
PD058197
CAS
137945-48-3
Tags
drug candidate
Drug indication
Cystic fibrosis
Rheumatoid arthritis
Diffuse systemic sclerosis
Systemic lupus erythematosus
dermatomyositis
Systemic sclerosis
Drug Status
investigational
Max Phase
3.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Ajulemic acid is a synthetic derivative of the non-psychoactive cannabinoid THC metabolite 11-nor-9-Carboxy-THC (PubChem CID 108207) . It is a non-selective cannabinoid receptor agonist . Ajulemic acid exhibits potentially useful analgesic and anti-inflammatory actions .
DESCRIPTION
Lenabasum (ajulemic acid) is a synthetic derivative of the non-psychoactive cannabinoid THC metabolite 11-nor-9-Carboxy-THC (PubChem CID 108207) . It is a non-selective cannabinoid receptor agonist . Lenabasum exhibits potentially useful analgesic and anti-inflammatory actions .
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
5
ChEMBL Drugs
DrugBank
DrugMAP
Guide to Pharmacology
Novartis Chemogenetic Library (NIBR MoA Box)
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
29
Molecular Weight
400.26
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
7
Ring Count
3
Aromatic Ring Count
1
cLogP
6.32
TPSA
66.76
Fraction CSP3
0.64
Chiral centers
2.0
Largest ring
6.0
QED
0.53
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Member status
virtual
MOA
CNR1 agonist
Cyclooxygenase-2 Inhibitors
IL-1beta Inhibitors
Lipoxygenase Inhibitors
Source data
