General
Preferred name
RELEBACTAM
Synonyms
MK-7655 ()
RELEBACTAM ANHYDROUS ()
Recarbrio-relebactam ()
(-)-relebactam monohydrate ()
Relebactam monohydrate ()
Relebactam hydrate ()
MK-7655 MONOHYDRATE ()
P&D ID
PD058102
CAS
1174018-99-5
Tags
available
covalent binder
drug
Approved by
PMDA
FDA
First approval
2019
Drug Status
investigational
approved
Drug indication
Bacterial infection
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Relebactam is a β-lactamase inhibitor .
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
18
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
EU-OPENSCREEN Bioactive Compound Library
Guide to Pharmacology
MedChem Express Bioactive Compound Library
Natural product-based probes and drugs
NCATS Inxight Approved Drugs
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
32
Molecular Weight
348.11
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
3
Rotatable Bonds
4
Ring Count
3
Aromatic Ring Count
0
cLogP
-1.14
TPSA
128.28
Fraction CSP3
0.83
Chiral centers
3.0
Largest ring
6.0
QED
0.55
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Microbiology/virology
Anti-infection
Target
??-Lactamase
Bacterial
Beta-lactamase
¦Â-Lactamase
MOA
beta lactamase inhibitor
Therapeutic Indication
Antibacterial
Therapeutic Class
Antimicrobial
Source data
