General
Preferred name
Nemadipine A
Synonyms
Nemadipine A ()
P&D ID
PD057230
CAS
54280-71-6
Tags
available
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Nemadipine A is a cell-permeable L-type calcium channel blocker. It was shown to reduce the expression of survivin, an inhibitor of the apoptosis protein (IAP) family of proteins, sensitizing TRAIL-resistant cancer cells to TRAIL.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
1
Compound Sets
2
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
10
Molecular Weight
419.12
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
1
Rotatable Bonds
5
Ring Count
2
Aromatic Ring Count
1
cLogP
3.74
TPSA
64.63
Fraction CSP3
0.37
Chiral centers
0.0
Largest ring
6.0
QED
0.34
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Source data
