General
Preferred name
SB-423562
Synonyms
NPSP-795 ()
SB-228357 ()
P&D ID
PD056887
CAS
351490-27-2
Tags
available
drug candidate
Drug indication
Osteoporosis
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Calcium sensing receptor negative allosteric modulator
(GtoPdb)
DESCRIPTION
SB-423562 is a short-acting calcium sensitive receptor (CaR) antagonist.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
9
BOC Sciences Bioactive Compounds
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
DrugMAP
Guide to Pharmacology
MedChem Express Bioactive Compound Library
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
16
Molecular Weight
436.24
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
3
Rotatable Bonds
11
Ring Count
3
Aromatic Ring Count
2
cLogP
3.49
TPSA
102.58
Fraction CSP3
0.46
Chiral centers
1.0
Largest ring
6.0
QED
0.5
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Target
CaSR
Solubility
Soluble in DMSO
Source data
