General
Preferred name
TYLOSIN
Synonyms
Fradizine ()
Tylosin A ()
Tylosine ()
Tylocine ()
Macrolides ()
Tylosin (phosphate) ()
Fradizine, Tylocine, Tylosine, Tylosin A ()
Tylosin phosphate ()
TYLOSIN TARTRATE ()
E713 ()
Tilosina ()
Tylan ()
TYLOCIN TARTARATE ()
P&D ID
PD055512
CAS
1401-69-0
1405-53-4
74610-55-2
Tags
available
drug
Approved by
FDA
Drug indication
Bacterial infection
Drug Status
vet_approved
approved
investigational
Max Phase
2.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Tylosin (Tylosin A) is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin is widely used as a feed additive for promoting animal growth. Tylosin is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle[1][2][3].
DESCRIPTION Tylosin phosphate is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin phosphate is widely used as a feed additive for promoting animal growth. Tylosin phosphate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle[1][2][3].
DESCRIPTION Tylosin (Tylosine) is a macrolide antibiotic obtained from cultures of Streptomyces fradiae. The drug is effective against many microorganisms in animals but not in humans. (TargetMol Bioactive Compound Library)
DESCRIPTION Tylosin tartrate, a macrolide antibiotic, is approved for the control of mycoplasmosis in poultry. (TargetMol Bioactive Compound Library)
Compound Sets
12
ChEMBL Drugs
CHEMBL42743
Drug Repurposing Hub
DrugBank
DB11475
DrugBank Approved Drugs
DB11475
DrugCentral
5642
DrugMAP
DM3BS97
DrugMAP Approved Drugs
DM3BS97
Guide to Pharmacology
13707
MedChem Express Bioactive Compound Library
HY-B0519A
HY-B0519B
ReFrame library
Selleckchem Bioactive Compound Library
tylosin
tylosin-phosphate
TargetMol Bioactive Compound Library
T1003
T0861
External IDs
38
Properties
(calculated by RDKit )
Molecular Weight
915.52
Hydrogen Bond Acceptors
18
Hydrogen Bond Donors
5
Rotatable Bonds
13
Ring Count
4
Aromatic Ring Count
0
cLogP
1.83
TPSA
238.67
Fraction CSP3
0.85
Chiral centers
21.0
Largest ring
16.0
QED
0.13
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
antibiotic
Bacterial
Antibiotics
Pathway
Microbiology&virology
Microbiology/virology
Anti-infection
Disease Area
infectious disease, gastroenterology
Indication
gram-positive bacterial infections, colitis
MOA
protein synthesis inhibitor
Source data