General
Preferred name
PD055467
Synonyms
1-Aminohydantoin (hydrochloride) ()
1-Aminohydantoin hydrochloride ()
P&D ID
PD055467
CAS
2827-56-7
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION 1-Aminohydantoin hydrochloride is a major metabolite of nitrofurantoin in animal tissues and can be used as a standard for the determination of residues of veterinary agents in meat, milk et.al. 1-Aminohydantoin hydrochloride covalently binds to tissue proteins and is released from the tissues under slightly acidic conditions and derivatized with 2-nitrobenzaldehyde to form nitrophenyl derivatives of AHD before detection[1].
PRICE 29
DESCRIPTION 1-Aminohydantoin hydrochloride is a significant metabolite of furantoin in animal tissues. It binds covalently to tissue proteins, is released under slightly acidic conditions, and can be detected by derivatization with 2-nitrobenzaldehyde forming a nitrophenyl derivative of AHD. It is used in assays to determine veterinary drug residues in meat and milk.
Compound Sets
2
MedChem Express Bioactive Compound Library
HY-Y0469
Selleckchem Bioactive Compound Library
1-aminohydantoin-hydrochloride
External IDs
10
Properties
(calculated by RDKit )
Molecular Weight
151.01
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
0
Ring Count
1
Aromatic Ring Count
0
cLogP
-1.17
TPSA
75.43
Fraction CSP3
0.33
Chiral centers
0.0
Largest ring
5.0
QED
0.26
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
Drug Metabolite
Pathway
Metabolic Enzyme/Protease
Source data