General
Preferred name
AXL 1717
Synonyms
Podophyllotoxin ()
picropodophyllin ()
P&D ID
PD055368
CAS
17434-18-3
4354-76-1
Tags
natural product
available
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
1
DrugMatrix
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
18
Properties
(calculated by RDKit )
Molecular Weight
414.13
Hydrogen Bond Acceptors
8
Hydrogen Bond Donors
1
Rotatable Bonds
4
Ring Count
5
Aromatic Ring Count
2
cLogP
2.41
TPSA
92.68
Fraction CSP3
0.41
Chiral centers
4.0
Largest ring
6.0
QED
0.76
Structural alerts
1
Tubulin modulation
Nuisance compounds in cellular assays
Custom attributes
(extracted from source data)
MOA
IGF-1R
Pathway
Tyrosine Kinase/Adaptors
Source data