General
Preferred name
(R)-Ketorolac
Synonyms
(+)-Ketorolac ()
P&D ID
PD054513
CAS
66635-93-6
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION (R)-Ketorolac is an orally active Cdc42 and Rac1 inhibitor. (R)-Ketorolac inhibits GTPase. (R)-Ketorolac alters ovarian cancer cell behaviors critical for invasion and metastasis. (R)-Ketorolac ameliorates cancer-associated cachexia[1][2][3].
PRICE 80
DESCRIPTION (R)-Ketorolac ((+)-Ketorolac) is the R-enantiomer of Ketorolac, with potent analgesic activity. (TargetMol Bioactive Compound Library)
Compound Sets
2
MedChem Express Bioactive Compound Library
HY-B0580B
TargetMol Bioactive Compound Library
T12624
External IDs
22
Properties
(calculated by RDKit )
Molecular Weight
255.09
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
3
Ring Count
3
Aromatic Ring Count
2
cLogP
2.29
TPSA
59.3
Fraction CSP3
0.2
Chiral centers
1.0
Largest ring
6.0
QED
0.86
QED
0.86
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Ras
Pathway
GPCR/G protein
MAPK/ERK Pathway
Source data