General
Preferred name
JD-5037
Synonyms
JD 5037 ()
JD5037 ()
P&D ID
PD053770
CAS
1392116-14-1
Tags
available
drug candidate
Drug indication
Diabetic complication
Obesity
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION JD5037 is a peripherally restricted (PR) cannabinoid-1 receptor blocker (CB1R antagonist). (GtoPdb)
Compound Sets
8
Concise Guide to Pharmacology 2021/22
10690
Concise Guide to Pharmacology 2023/24
10690
Drug Repurposing Hub
DrugMAP
DMTGI64
Guide to Pharmacology
10690
MedChem Express Bioactive Compound Library
HY-18697
Selleckchem Bioactive Compound Library
id-5037
TargetMol Bioactive Compound Library
T4453
External IDs
20
Properties
(calculated by RDKit )
Molecular Weight
571.12
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
2
Rotatable Bonds
7
Ring Count
4
Aromatic Ring Count
3
cLogP
4.64
TPSA
117.22
Fraction CSP3
0.22
Chiral centers
2.0
Largest ring
6.0
QED
0.32
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Neuronal Signaling
Target
CB1R
MOA
Cannabinoid Receptor
Cannabinoid Receptor antagonist
Source data