General
Preferred name
Norverapamil (hydrochloride)
Synonyms
(¡À)-Norverapamil hydrochloride ()
D591 hydrochlorid ()
(±)-Norverapamil hydrochloride ()
D591 hydrochloride ()
(¡À)-Norverapamil (hydrochloride) ()
(±)-Norverapamil (hydrochloride) ()
D591 (hydrochloride) ()
Norverapamil hydrochloride ()
Norverapamil (6%) ()
NORVERAPAMIL ()
P&D ID
PD053668
CAS
67018-85-3
67812-42-4
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Norverapamil hydrochloride ((¡À)-Norverapamil hydrochloride), an N-demethylated metabolite of Verapamil, is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor[1][2].
PRICE 189
DESCRIPTION Norverapamil hydrochloride (D591 hydrochloride) ((??)-Norverapamil hydrochloride) is an N-demethylated metabolite of Verapamil and it is an L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor.
DESCRIPTION Norverapamil hydrochloride (D591 hydrochloride) ((±)-Norverapamil hydrochloride) is an N-demethylated metabolite of Verapamil and it is an L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor. (TargetMol Bioactive Compound Library)
Compound Sets
3
Cayman Chemical Bioactives
20950
MedChem Express Bioactive Compound Library
HY-100750
TargetMol Bioactive Compound Library
T16339
External IDs
28
Properties
(calculated by RDKit )
Molecular Weight
440.27
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
1
Rotatable Bonds
13
Ring Count
2
Aromatic Ring Count
2
cLogP
4.75
TPSA
72.74
Fraction CSP3
0.5
Chiral centers
1.0
Largest ring
6.0
QED
0.45
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Calcium Channel
Drug Metabolite
P-gp (P-glycoprotein)
P-glycoprotein
Pathway
Membrane Transporter/Ion Channel
Metabolism
Neuroscience
Metabolic Enzyme/Protease
Neuronal Signaling
Source data