General
Preferred name
Chloraminophenamide
Synonyms
4-amino-6-chlorobenzene-1,3-disulfonamide ()
4-Amino-6-chloro-1,3-benzenedisulfonamide ()
P&D ID
PD053534
CAS
121-30-2
1184995-49-0
Tags
available
drug candidate
Drug indication
Discovery agent
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Chloraminophenamide (Compound 14) is a carbonic anhydrase inhibitor, with Kis of 75, 160 and 8400 nM for hCA II, bCA IV and hCA I, respectively. Chloraminophenamide has the potential for antiglaucoma research[1].
DESCRIPTION Chloraminophenamide is a carbonic anhydrase inhibitor. (Enamine Bioactive Compounds)
Cell lines
0
Organisms
3
Compound Sets
7
Cayman Chemical Bioactives
21309
DrugMAP
DMIWGZS
Enamine Bioactive Compounds
EBC-04111
EU-OPENSCREEN Bioactive Compound Library
EOS102028
Mcule NIBR MoA Box Subset
MCULE-6845641116
MedChem Express Bioactive Compound Library
HY-W031519
Novartis Chemogenetic Library (NIBR MoA Box)
External IDs
27
Properties
(calculated by RDKit )
Molecular Weight
284.96
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
3
Rotatable Bonds
2
Ring Count
1
Aromatic Ring Count
1
cLogP
-0.78
TPSA
146.34
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.61
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Member status
virtual
MOA
Carbonic Anhydrase Type II Inhibitors
Target
Carbonic Anhydrase
Pathway
Metabolic Enzyme/Protease
Source data