General
Preferred name
α-Solanine
Synonyms
alpha-Solanine ()
Solanine alpha ()
¦Á-Solanine ()
??-Solanine ()
P&D ID
PD053429
CAS
20562-02-1
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION ¦Á-solanine, a bioactive component and one of the major steroidal glycoalkaloids in Solanum nigrum, has been observed to inhibit growth and induce apoptosis in cancer cells[1].
PRICE 404
DESCRIPTION ??-Solanine (alpha-Solanine) is an alkaloid derived from potato with anticancer and antitumor activity, attenuating chondrocyte death by inhibiting the NF-??B pathway. ??-Solanine inhibits the proliferation and migration of glioma cells but promotes apoptosis of glioma cells.
DESCRIPTION α-Solanine (alpha-Solanine) is an alkaloid derived from potato with anticancer and antitumor activity, attenuating chondrocyte death by inhibiting the NF-κB pathway. α-Solanine inhibits the proliferation and migration of glioma cells but promotes apoptosis of glioma cells. (TargetMol Bioactive Compound Library)
Compound Sets
2
MedChem Express Bioactive Compound Library
HY-N6602
TargetMol Bioactive Compound Library
TN1376
External IDs
26
Properties
(calculated by RDKit )
Molecular Weight
867.5
Hydrogen Bond Acceptors
16
Hydrogen Bond Donors
9
Rotatable Bonds
8
Ring Count
9
Aromatic Ring Count
0
cLogP
0.16
TPSA
240.69
Fraction CSP3
0.96
Chiral centers
26.0
Largest ring
6.0
QED
0.15
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
NF-κB
Apoptosis
Akt
Autophagy
COX
MMP
MTOR
NO Synthase
Pathway
Immunology/Inflammation
Metabolic Enzyme/Protease
PI3K/Akt/mTOR
NF-¦ÊB
Source data