General
Preferred name
ANAMORELIN
Synonyms
Anamorelin (Fumarate) ()
ONO-7643 Fumarate ()
RC1291 Fumarate ()
RC-1291 hydrochloride ()
ONO-7643 hydrochloride ()
RC-1291 ()
ONO-7643 ()
ANAMORELIN HYDROCHLORIDE ()
Anamorelin (hydrochloride) ()
RC-1291 (hydrochloride) ()
ONO-7643 (hydrochloride) ()
ONO-7643, RC-1291, ST-1291 ()
ST-1291 ()
Anamorelina ()
Anamoreline ()
Anamorelin hcl ()
RC-1291 HCl ()
P&D ID
PD052417
CAS
861998-00-7
249921-19-5
Tags
available
drug
drug candidate
Approved by
PMDA
First approval
2021
Drug indication
Carbohydrate metabolism disorder
non-small cell lung carcinoma
Cachexia
Drug Status
approved
investigational
Max Phase
3.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Anamorelin (RC-1291) is a potent ghrelin receptor agonist with EC50 value of 0.74 nM in the FLIPR assay.
PRICE
83
DESCRIPTION
Anamorelin (RC-1291) hydrochloride is a potent ghrelin receptor agonist with EC50 value of 0.74 nM in the FLIPR assay.
PRICE
102
DESCRIPTION
Anamorelin (ONO-7643) is a novel ghrelin receptor agonist (EC50: 0.74 nM in the FLIPR assay).
(TargetMol Bioactive Compound Library)
DESCRIPTION
AnaMorelin hydrochloride (RC-1291 hydrochloride) is a novel ghrelin receptor agonist(EC50 : 0.74 nM, in the FLIPR assay).
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
14
AdooQ Bioactive Compound Library
Cayman Chemical Bioactives
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugCentral
DrugCentral Approved Drugs
DrugMAP
Guide to Pharmacology
Other bioactive compounds
ReFrame library
Selleckchem Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
45
Molecular Weight
546.33
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
3
Rotatable Bonds
9
Ring Count
4
Aromatic Ring Count
3
cLogP
2.72
TPSA
114.77
Fraction CSP3
0.45
Chiral centers
2.0
Largest ring
6.0
QED
0.36
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Ghrelin receptor
GHS-R
GHSR
MOA
growth hormone secretagogue receptor agonist
Pathway
GPCR/G protein
Source data
