General
Preferred name
Rose bengal lactone
Synonyms
Robengatope I-131 ()
Rose bengal (131i) sodium ()
Rose Bengal Sodium (131I) ()
Robengatope ()
Sodium Rose Bengal (131I) ()
ROSE BENGAL ()
Provecta ()
ROSE BENGAL SODIUM ()
Rose Bengal ()
Rose Bengal (sodium salt) ()
P&D ID
PD052288
CAS
152-74-9
127695-05-0
157367-41-4
632-69-9
Tags
available
drug candidate
Drug Status
experimental
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Rose Bengal sodium is a potent inhibitor of VGlut and vesicular monoamine transporter (VMAT) (Ki of 19 and 64 nM for VGlut andVMAT, respectively）
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
9
Cayman Chemical Bioactives
Drug Repurposing Hub
DrugBank
DrugMatrix
LSP-MoA library (Laboratory of Systems Pharmacology)
Other bioactive compounds
ReFrame library
TargetMol Bioactive Compound Library
ZINC Tool Compounds
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
37
Molecular Weight
971.5
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
2
Rotatable Bonds
0
Ring Count
5
Aromatic Ring Count
3
cLogP
8.7
TPSA
75.99
Fraction CSP3
0.05
Chiral centers
0.0
Largest ring
6.0
QED
0.1
Structural alerts
2
aggregator (Aggregator Advisor)
Aggregators
aggregator (ZINC)
Aggregators
Related compounds
Custom attributes
(extracted from source data)
Target
Influenza Virus
vesicular monoamine transporter (VMAT)
Indication
staining agent
MOA
coloring agent
Pathway
Membrane Transporter/Ion Channel
Microbiology/virology
Source data
