General
Preferred name
TILUDRONATE DISODIUM
Synonyms
Tiludronate (disodium) ()
Tiludronic acid (disodium) ()
Tiludronic acid disodium salt ()
SR-41319B ()
Skelid ()
Tiludronate disodium anhydrous ()
Tiludronate sodium ()
SR 41319B ()
P&D ID
PD052072
CAS
149845-07-8
Tags
available
drug
Drug Status
approved
Max Phase
Phase 4
Drug indication
Paget's Disease Treatment
Osteoporosis Treatment And Prevention
First approval
1997
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
The disodium salt form of Tiludronic acid which has been found to be a biphosphonate bone resorption inhibitor and could be used against osteitis deformans.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
4
BOC Sciences Bioactive Compounds
ChEMBL Approved Drugs
ChEMBL Drugs
MedChem Express Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
20
Molecular Weight
361.89
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
2
Rotatable Bonds
4
Ring Count
1
Aromatic Ring Count
1
cLogP
-5.18
TPSA
120.72
Fraction CSP3
0.14
Chiral centers
2.0
Largest ring
6.0
QED
0.31
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Membrane Transporter/Ion Channel
Target
Proton Pump
Source data
