General
Preferred name
CHLOPHEDIANOL HYDROCHLORIDE
Synonyms
Chlophedianol (hydrochloride) ()
Clofedanol (hydrochloride) ()
Calmotusin (hydrochloride) ()
NSC 113595 (hydrochloride) ()
Clofedanol hydrochloride ()
Coldrin ()
Chlophedianol hcl ()
SL 501 ()
Ulone ()
Ulo ()
SL-501 ()
Pectolitan ()
BAYER-186 ()
Sk-74 ()
P&D ID
PD051950
CAS
511-13-7
Tags
available
drug
Drug Status
approved
Max Phase
4.0
First approval
1982
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Chlophedianol (Clofedanol) hydrochloride is an orally active and potent antitussive agent. Chlophedianol hydrochloride can be used for the research of acute cough due to upper respiratory tract infections (URIs)[1][2].
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
3
ChEMBL Approved Drugs
ChEMBL Drugs
MedChem Express Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
17
Molecular Weight
325.1
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
5
Ring Count
2
Aromatic Ring Count
2
cLogP
3.95
TPSA
23.47
Fraction CSP3
0.29
Chiral centers
1.0
Largest ring
6.0
QED
0.9
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Sigma Receptor
Pathway
Neuronal Signaling
Source data
