General
Preferred name
D-AP4
Synonyms
P&D ID
PD051867
CAS
78739-01-2
6323-99-5
20263-07-4
Tags
available
drug candidate
Drug indication
Discovery agent
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
D-AP4 has been found to be an excitatory amino acid receptor antagonist as well as an agonist at the quisqualate-sensitized AP6 site.
(BOC Sciences Bioactive Compounds)
DESCRIPTION
Selective NMDA antagonist
(Tocris Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
5
BOC Sciences Bioactive Compounds
DrugMAP
Guide to Pharmacology
Tocris Bioactive Compound Library
ZINC Tool Compounds
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
16
Molecular Weight
183.03
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
4
Rotatable Bonds
4
Ring Count
0
Aromatic Ring Count
0
cLogP
-1.03
TPSA
120.85
Fraction CSP3
0.75
Chiral centers
1.0
Largest ring
0.0
QED
0.41
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Primary Target
Non-selective Ionotropic Glutamate
MOA
Antagonist
Source data
