General
Preferred name
methamphetamine
Synonyms
METHAMPHETAMINE (-) ()
METHAMPHETAMINE (+) ()
METHAMPHETAMINE HYDROCHLORIDE, DL- ()
(±)-Methamphetamine-d5 (hydrochloride) ()
(±)-Methamphetamine-d14 (hydrochloride) ()
(±)-Methamphetamine-d9 (hydrochloride) ()
(±)-Methamphetamine-d6 (hydrochloride) ()
(±)-Methamphetamine (hydrochloride) ()
P&D ID
PD051719
CAS
30639-16-8
7632-10-2
51-57-0
300-42-5
4298-16-2
2747917-87-7
2714414-13-6
1219805-48-7
1219805-26-1
Tags
natural product
drug
available
Drug Status
approved
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Methamphetamine refers to the racemic free base mixture of the dextromethamphetamine (PubChem CID 10836) and levomethamphetamine (PubChem CID 36604) stereo-isomers. We show the structure without specified stereochemistry to represent the mixture. Methamphetamine use as a sympathomimetic has been largely replaced by safer substitutes with comparable clinical efficacy, but reduced propensity for serious side-effects and illicit recreational use. The production, distribution, sale, and possession of methamphetamine is restricted or illegal in many jurisdictions.
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
9
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
DrugMatrix
Guide to Pharmacology
Ki Database
NCATS Inxight Approved Drugs
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
42
Molecular Weight
149.12
Hydrogen Bond Acceptors
1
Hydrogen Bond Donors
1
Rotatable Bonds
3
Ring Count
1
Aromatic Ring Count
1
cLogP
1.84
TPSA
12.03
Fraction CSP3
0.4
Chiral centers
1.0
Largest ring
6.0
QED
0.69
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Source data
