General
Preferred name
Org 12962
Synonyms
Org-12962 ()
Org 12962 hydrochloride ()
ORG 12962 (hydrochloride) ()
P&D ID
PD051703
CAS
132834-56-1
210821-63-9
Tags
available
drug candidate
Drug indication
Discovery agent
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Org 12962 hydrochloride is a 5-HT2C receptor agonist with pEC50 value of 7.01. It shows antiaversive effects in the anxiety models in rats.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
8
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
Drug Repurposing Hub
DrugMAP
EU-OPENSCREEN Bioactive Compound Library
Guide to Pharmacology
MedChem Express Bioactive Compound Library
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
24
Molecular Weight
265.06
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
1
Ring Count
2
Aromatic Ring Count
1
cLogP
2.16
TPSA
28.16
Fraction CSP3
0.5
Chiral centers
0.0
Largest ring
6.0
QED
0.79
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
HTR2A, HTR2B, HTR2C
5-HT Receptor
MOA
serotonin receptor agonist
Pathway
GPCR/G protein
Neuronal Signaling
Source data
